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Centre for Trophoblast Research

 

Does 2D-Histologic identification of villous types of human placentas at birth enable sensitive and reliable interpretation of 3D structure?

Does 2D-Histologic identification of villous types of human placentas at birth enable sensitive and reliable interpretation of 3D structure? A recent paper of the same name suggests inter rater variability is high and indicates substantial observer influence on the outcome of histologic assessments. Cross-match of villous types with the predetermined positions of villous branches of villous trees revealed substantial mismatch between the outcome of stromal classification and 3D-position of the sectioned villi in the placental villous trees.

A special supplement of the American Journal of Obstetrics and Gynecology dedicated to the placenta has just been published http://www.ajog.org/issue/S0002-9378(15)X0002-0. Authors include CTR Director Graham Burton and CTR Scientific Advisory Board member John Kingdom.

We are delighted to welcome our latest CTR Graduate Students, Lorenzo Orietti and Iva Filipovic. Iva has just completed her MSc in Immunology at Imperial College London. She recently received the Richard Batchelor prize, awarded to the student with the best performance in the MSc. Immunology course. The student to whom the prize is awarded is chosen by the Board of Examiners and is based predominantly on examination and thesis/viva performance. Well done Iva!