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Centre for Trophoblast Research



Abumaree MH, Brownbill P, Burton G, Castillo C, Chamley L, Croy BA, Drewlo S, Dunk C, Girard S, et al. (2013) IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta. Feb 2014. J.Placenta S15-S19. Doi: 10.1016/j.placenta.2013.11.009.

Aiken CE, Fowden AL, Smith GC. (2014) Antenatal glucocorticoids prior to cesarean delivery at term. JAMA Pediatr 168(6):507-508 Jun 2014. Doi: 10.1001/jamapediatrics.2014.9.

Alfaradhi MZ, Fernandez-Twinn DS, Martin-Gronert MS, Musial B, Fowden A, Ozanne SE. (2014) Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity. Am J Physiol Regul Integr Comp Physiol 307(1):R26-R34 01.  Doi: 10.1152/ajpregu.00049.2014.

Babor F, Manser AR, Fischer JC, Scherenschlich N, Enczmann J, Chazara O, Moffett A, Borkhardt A, Meisel R, Uhrberg M. (2014) KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse. Blood 124(14):2248-2251 02 Oct 2014. Doi: 10.1182/blood-2014-05-572065.

Burton GJ, Sebire NJ, Myatt L, Tannetta D, Wang Y-L, Sadovsky Y, Staff AC, Redman CW. (2014) Optimizing sample collection for placental research. Placenta 35, 9-22.

Cambuli F, Murray A, Dean W, Dudzinska D, Krueger F, Andrews S, Senner CE, Cook SJ, Hemberger M. (2014) Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast  Nat Commun 5:5538 2014. doi: 10.1038/ncomms6538.

Carr SK, Chen JH, Cooper WN, Constância M, Yeo GS, Ozanne SE (2014) Maternal diet amplifies the hepatic aging trajectory of Cidea in male mice and leads to the development of fatty liver. FASEB J 28(5):2191-2201 May 2014. Doi: 10.1096/fj.13-242727.

Cindrova-Davies T (2014) The therapeutic potential of antioxidants, ER chaperones, NO and H2S donors, and statins for treatment of preeclampsia. Front Pharmacol 5:119 2014. Doi: 10.3389/fphar.2014.00119.

Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Affara NA, et al. (2014) DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: Results of a pilot randomized controlled trials. World Review of Nutrition and Dietetics 109:2-3 2014. Doi: 10.1159/000356352.

Francesco Colucci, Ashley Moffett. (2014) Uterine NK cells: active regulators at the maternal-fetal interface. J Clin Invest. 124(5):1872-9. doi: 10.1172/JCI68107.

Colucci F, Moffett A, Trowsdale J (2014) Medawar and the immunological paradox of pregnancy: 60 years on. Eur J Immunol 44(7):1883-1885 Jul 2014. DOI: 10.1002/eji.201470065.

Farrell LE, Hiby SE, Apps R, Chazara O, Trogstad L, Gjessing HK, Magnus P, Carrington M, Moffett A. (2014) KIR and HLA-C: Immunogenetic regulation of human birth weight. Norsk Epidemiologi 24(1-2):107-110 2014.

Ficz G, Reik W (2013) Reprogramming by cell fusion: boosted by Tets. Mol Cell 49(6):1017-1018 28 Mar 2013. Doi: 10.1016/j.molcel.2013.03.014.

Fowden AL, Forhead AJ, Sferruzzi-Perri AN, Burton GJ, Vaughan OR. (2014) Review: Endocrine regulation of placental phenotype. Placenta 03 Dec 2014. Doi: 10.1016/j.placenta.2014.11.018.

Franchini DM, Chan CF, Morgan H, Incorvaia E, Rangam G, Dean W, Santos F, Reik W, Petersen-Mahrt SK (2014) Processive DNA demethylation via DNA deaminase-induced lesion resolution. PLoS One 9(7):e97754 2014. Doi: 10.1371/journal.pone.0097754.

Giussani DA, Niu Y, Herrera EA, Richter HG, Camm EJ, Thakor AS, Kane AD, Hansell JA, Brain KL, Skeffington KL, Itani N, Wooding FBP, Cross CM, Allison BJ. (2014) Heart disease link to fetal hypoxia and oxidative stressAdvances in Experimental Medicine and Biology Volume 814, 2014, pp 77-87.

Graham SJ, Wicher KB, Jedrusik A, Guo G, Herath W, Robson P, Zernicka-Goetz M (2014) BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryoNat Commun 5:5667 2014. doi:10.1038/ncomms6667.

Hanna CW, Kelsey G. (2014) The specification of imprints in mammals. Heredity 113(2):176-183 2014. Doi: 10.1038/hdy.2014.54.

Hiby SE, Apps R, Chazara O, Farrell LE, Magnus P, Trogstad L, Gjessing HK, Carrington M, Moffett A (2014) Maternal KIR in Combination with Paternal HLA-C2 Regulate Human Birth Weight. Journal of Immunology, vol. 192 no. 11 5069-5073.

Kato Y, Oyen ML, Burton GJ. (2014) Placental villous tree models for evaluating the mechanical environment in the human placenta. Systems and Techniques, Proceedings.Institute of Electrical and Electronics Engineers Inc. 107-111. 14 Nov 2014. Doi: 10.1109/IST.2014.6958455.

Kubaczka C, Senner C, Araúzo-Bravo MJ, Sharma N, Kuckenberg P, Becker A, Zimmer A, Brüstle O, Peitz M, et al. (2014) Derivation and maintenance of murine trophoblast stem cells under defined conditions. Stem Cell Reports 2(2):232-242 11 Feb 2014. Doi: 10.1016/j.stemcr.2013.12.013.

Lee HJ, Hore TA, Reik W (2014) Reprogramming the methylome: erasing memory and creating diversity. Cell Stem Cell 14(6):710-719 05 Jun 2014.  Doi: 10.1016/j.stem.2014.05.008.

Kieckbusch J, Gaynor LM, Moffett A, Colucci F. (2014)  MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodellingNat Comm. 28;5:3359. doi: 10.1038/ncomms4359.

Peat JR, Dean W, Clark SJ, Krueger F, Smallwood SA, Ficz G, Kim JK, Marioni JC, Hore TA, Reik W. (2014) Genome-wide Bisulfite Sequencing in Zygotes Identifies Demethylation Targets and Maps the Contribution of TET3 Oxidation. Cell Reports 9(6):1990-2000 24 Dec 2014. Doi: 10.1016/j.celrep.2014.11.034.

Moffett A, Colucci F.  (2014) Uterine Natural Killer cells: Active Regulators at the Maternal-Fetal Interface. Journal of Clinical Investigation (in press).

Nakimuli A, Chazara O, Byamugisha J, Elliott AM, Kaleebu P, Mirembe F, Moffett A. (2014) Pregnancy, parturition and preeclampsia in women of African ancestry. American Journal of Obstetrics and Gynecology 210(6) 2014. 10.1016/j.ajog.2013.10.879.

Quilter CR, Cooper WN, Cliffe KM, Skinner BM, Prentice PM, Nelson L, Bauer J, Ong KK, Constância M, Lowe WL, Affara NA, Dunger DB (2014) Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk. FASEB J 28(11):4868-4879 Nov 2014. Doi: 10.1096/fj.14-255240.

Reik W, Kelsey G. (2014) Epigenetics: Cellular memory erased in human embryos. Nature 511(7511):540-541 31 Jul 2014. Doi: 10.1038/nature13648.

Roper SJ, Chrysanthou S, Senner CE, Sienerth A, Gnan S, Murray A, Masutani M, Latos P, Hemberger M. (2014) ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells. Nucleic Acids Res 42(14):8914-8927 Aug 2014. DOI: 10.1093/nar/gku591.

Saksouk N, Barth TK, Ziegler-Birling C, Olova N, Nowak A, Rey E, Mateos-Langerak J, Urbach S, Reik W, et al. (2014) Redundant mechanisms to form silent chromatin at pericentromeric regions rely on BEND3 and DNA methylation. Mol Cell 56(4):580-594 20 Nov 2014. DOi: 10.1016/j.molcel.2014.10.001.

Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, Peat J, Andrews SR, Stegle O, Reik W, Kelsey G.  (2014) Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. Nature Methods 11(8):817-820 2014. Doi: 10.1038/nmeth.3035.

Teoh PJ, Menzies FM, Hansell CA, Clarke M, Waddell C, Burton GJ, Nelson SM, Nibbs RJ. (2014) Atypical chemokine receptor ACKR2 mediates chemokine scavenging by primary human trophoblasts and can regulate fetal growth, placental structure, and neonatal mortality in mice. J Immunol 193(10):5218-5228. doi: 10.4049/jimmunol.1401096.

Yung HW, Colleoni F, Atkinson D, Cook E, Murray AJ, Burton GJ, Charnock-Jones DS. (2014) Influence of speed of sample processing on placental energetics and signalling pathways: implications for tissue collection. Placenta 35,103-108.

Yung HW, Atkinson D, Campion-Smith T, Olovsson M, Charnock-Jones DS and Burton GJ. (2014) Differential activation of placental Unfolded Protein Response pathways implies heterogeneity of causation of early- and late-onset pre-eclampsia. Journal of Pathology, in press.