Research
My research is focused on determine how environmental factors impact pregnancy outcomes. I have been working with guinea pig, mouse, sheep and human models, exploring the effects of hypoxia, high-fat high-sugar diet and exercise in maternal, placental and foetal health. Adding to my laboratory experience, I have been involved in community interventions and qualitative studies looking for alternatives to translate the basic knowledge to real life settings.
Publications
Candia AA, Skow RJ, Quon A, Steinback C, Davidge ST, Davenport MH. Circulating miRNA levels following a 14-week aerobic exercise intervention during pregnancy: A secondary exploratory analysis of the PEACH RCT. J appl Physiol (1985). May 2025. https://pubmed.ncbi.nlm.nih.gov/40353725/
Candia AA, Lean SC, Zhang CXW, McKeating DR, Cochrane A, Gulacsi E, Herrera EA, Krause BJ, Sferruzzi-Perri AN. Obesogenic diet in mice leads to inflammation and oxidative stress in the mother in association with sex-specific changes in fetal development, inflammatory markers and placental transcriptome. Antioxidants (Basel). March 2024. https://pubmed.ncbi.nlm.nih.gov/38671859/
Zhang CXW, Candia AA, Sferruzzi-Perri AN. Placental inflammation, oxidative stress, and fetal outcomes in maternal obesity. Trends Endocrinol Metab. February 2024.
https://pubmed.ncbi.nlm.nih.gov/38418281/
Candia AA, Jiménez T, Navarrete A, Beñaldo F, Silva P, GarcÃa-Herrera C, Sferruzzi-Perri AN, Krause BJ, González-Candia A, Herrera EA. Developmental ultrasound characteristics in guinea pigs: similarities with human pregnancy. Veterinary Science. February 2023. https://pubmed.ncbi.nlm.nih.gov/36851448/
Candia AA, Arias PV, Gonzalez-Candia C, Navarrete A, Ebensperger G, Reyes RV, Llanos AJ, Gonzalez-Candia A, Herrera EA. Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function. Vascular Pharmacology. June 2022. https://pubmed.ncbi.nlm.nih.gov/35150933/
