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Research

I am a postdoctoral researcher working in the labs of Dr Naomi McGovern and Prof. Catherine Aiken. In this role, I will be investigating host-pathogen interactions in organoid models of the human placenta, particularly infection with Listeria monocytogenes. I have previously completed a PhD in biomedical engineering at Queen Mary, University of London, in which I developed and characterised microfluidic in vitro models of the human eccrine sweat gland. Prior to this, I completed a MBiomedSci at the University of Sheffield, where I investigated transcriptomic changes in a microfluidic in vitro  model of the renal proximal tubule in Lowe Syndrome. I am interested in research on 3D in vitro modelling of human epithelia, modelling immune responses in vitro, epithelial physiology, and biomaterials for 3D in vitro models.  

Publications

Key publications: 

Hindle, S.A., Bachas Brook, H., Chrysanthou, A., Chambers, E.S., Caley, M.P. and Connelly, J.T., 2024. Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent. Advanced Science, p.2415717. https://doi.org/10.1002/advs.202415717

Postdoctoral Research Associate
Dept. of Pathology; Obstetrics and Gynaecology
Research Groups: Naomi McGovern, Catherine Aiken
Holly Bachas Brook

Affiliations