Providing bioinformatics support for the groups within the CTR. Examples of supported bioinformatics:
- Single cell
- whole genome/targetted
- methylation (mC and hmC)
- RNA structure prediction (2D & 3D) and motif discovery
- Protein alignments, structure prediction and interaction analysis
Before joining the CTR I worked at Cambridge Epigenetix (CEGX) as a bioinformatician working on the development of epigenetics tools to enable single base resolution sequencing of methyl-cytosine (mC) and hydroxymethyl-cytosine (hmC). Prior to this I was a senior postdoc in the Department of Biochemistry at University of Oxford, working on the RNA structural motifs required for mRNA localization and their interaction with trans-acting protein factors. I developed a wide range of novel bioinformatics and computational biology approaches, including high throughput RNA sequence analysis, microscope image analysis, RNA structure prediction and genome wide motif searches.
Cambridge Big Data: