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CTR Journal Club

Journal club sessions occur every second and fourth Wednesday of each month at 4:00pm. Everyone is welcome to attend!


The goal of the CTR Journal Club is to discuss cutting edge research articles focusing on the cellular and molecular biology of placental development and function, not only in humans but also in model organisms and cell culture systems. This includes the following topics: epigenetic regulation, lineage specification, implantation, trophoblast differentiation, placental structure and function, and maternal-fetal interactions during pregnancy.

The journal club provides CTR members and other researchers alike with a friendly environment to familiarize themselves with the current literature, to critique experimental design and to have informal discussions about the "Big Picture" regarding the biology of the trophoblast lineage, the placenta and pregnancy.

Everyone is welcome to attend the CTR journal club! You do not need to be a CTR member.


Next meeting 

The next CTR journal club meeting will take place on the 26th April 2017 at 4pm in the Hodgkin-Huxley seminar room, Physiology Building (Downing Site).



If you have any questions or you would like to attend or present at the CTR journal club, please contact Erica Watson.


How does the Journal Club work and who can join in the discussion?


2016-2017 Schedule


DatePresenterArticle Presented/To Be PresentedLocation*


Mick Elliot         

Park et al., 2016. Cis-Regulatory Evolution of Forkhead Box O1 (FOXO1), a Terminal Selector Gene for Decidual Stromal Cell Identity. Molecular Biology and Evolution 33(12): 3161-3169.  



Francesca Gaccioli   Burke et al, 2016. Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia. The Journal of Clinical Investigation 126(7): 2561-74.
23-11-2016 Jens Kieckbusch     

Chakraborty et al, 2016. HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia. PNAS 113(46): E7212-E7221.



Elisa Balmas        

Bertero et al, 2016. Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro study of human development using hPSCs. Development 143: 4405-18.




 Christmas break



Tasneem     Pope Rhee et al, 2017. ARID3A is required for mammalian placental development. Developmental Biology 422(2): 83-91.


Norman Shreeve Wu et al, 2017. Interspecies chimerism with pluripotent stem cells. Cell 168(3): 473-486.e15. Add


Iva Filipovic        Nelson et al, 2016. Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy. Nature Communications 7(11414): 1-12. HH

Malwina       Prater

Hanna et al, 2016. Pervasive polymorphic imprinted methylation in the human placenta. Genome Research 26(6): 756-767. HH

Nadia Capatina      

Brosens et al, 2014. Uterine selection of human embryos at implantation. Scientific Reports 4: 3894. Add 

Easter Break

26-04-2017 Olympe Chazara      


10-05-2017 Margherita Turco    



* Meeting venues: HH = Hodgkin-Huxley Seminar Room, Physiology Building (Downing Site); Add = Seminar room, Postdoc Centre, Biomedical Campus, Addenbrookes.

Articles presented in 2015-2016

Articles presented in 2014-2015

Articles presented in 2013-2014

Articles presented in 2012-2013

Articles presented in 2011-2012

Articles presented in 2010-2011