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Francesca Gaccioli

Research Associate


Office Phone: +44 (0)1223 336877

Research Interests

Research summary
The aim of my project is to characterize epigenetic regulatory mechanisms and transcript profiles in placental samples obtained from pathological and uncomplicated pregnancies. The study will be performed using a unique collection of placental samples obtained from optimally phenotyped cases of human fetal growth restriction and matched controls from the same prospective cohort of ~4500 women. Furthermore we aim to identify biomarkers for fetal growth restriction in the maternal blood using serum and plasma samples from the same cohort, obtained serially through the pregnancy. The project has the potential to generate new knowledge on the biological basis of intra-uterine growth restriction and to identify novel biomarkers for clinical applications.

 

Funding: NIHR