Twinning can be associated with intertwin growth discrepancy. A new paper, done in twin, shows that differences in placental structure can be the cause for such discrepancy.

 • Twinning and placental fusion occur at a low frequency in species, like mice.

• In this case report we show that placental fusion is linked with changes in the structure of the mouse placenta.

• Morphological changes are seen in both the exchange and endocrine regions of the placenta.

• There are also elevated levels of calcification in the placenta.

• Alterations in the fused placenta at least partly explain the intertwin growth discrepancy.

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