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PhD Projects on offer

 Current PhD projects.

Listed below are the current PhD projects available:

 

 

 

 

 

 

 

 

Developmental origins of heart disease Supervisor: Professor Dino A. Giussani, Department of Physiology Development and Neuroscience

 Mitochondrial function during pregnancy in a model of abnormal folate metabolism Supervisors: Dr Erica Watson and Dr Andrew Murray

Computational analysis of next-generation sequencing methylation data Supervisor: Dr Russell Hamilton. Co-supervised by Prof. Richard Samworth

Novel regulators of trophoblast stem cell potential
Supervisor: Dr Myriam Hemberger

Embryonic and extraembryonic partnership: requisite for successful pregnancy
Supervisor: Professor Magdalena Zernicka-Goetz 

An Evolutionary Approach to Understanding Transcriptional Control in the Human Placenta
Supervisor: Professor Steve Charnock-Jones.
Co-supervised by Dr Paul Flicek, European Bioinformatics Institute (EBI, Hinxton)

Single cell sequencing of the placenta
Supervisor: Professor Steve Charnock-Jones

Understanding the nature and role of placental endocrine function in materno-fetal resource allocation during pregnancy
Supervisor: Dr Amanda Sferruzzi-Perri

Genetic and molecular mechanisms of placental angiogenesis 
Supervisor: Dr Miguel Constância

Placental endoplasmic reticulum stress in maternal endothelial dysfunction; a model for pre-eclampsia.
Supervisor: Professor Graham J Burton and Dr HW Yung

Improving placental energy metabolism and obstetric outcome in pathological pregnancies – lessons from high-altitude populations
Supervisor: Dr Andrew Murray

Deciphering the role of the imprinted gene Rtl1/Peg11 in the placenta
Supervisor: Professor Anne Ferguson-Smith & Dr Mitsuteru Ito

Placento-fetal hypoxia and preeclampsia
Supervisor: Professor Dino Giussani

Microfluidic devices for the study of human trophoblast invasion
Supervisors: Dr Michelle Oyen and Professor Graham Burton

Manipulating epigenetic reprogramming in vivo and its role in extraembryonic tissue function
Supervisor:   Professor Wolf Reik

How is offspring immunity set during development?
Supervisors: Dr Jens Kieckbusch / Dr Francesco Colucci

Developmental Regulation of the Placental Prolactin-Growth Hormone Gene Families in the Placenta
Supervisors:  Abigail L. Fowden and Amanda Sferruzzi-Perri,