Dr Denise Fernandez-Twinn

I am interested in how pregestational obesity predisposes metabolic and cardiovascular disease in offspring. My studies in a murine model of maternal obesity during gestation currently explore intervention approaches to uncover underlying mechanisms responsible for adverse metabolic and cardiovascular outcomes and investigate the efficacy of these interventions for translational therapy. I am currently investigating maternal metabolic and cardiovascular dysfunction as potential drivers of preeclampsia, placental dysfunction and its consequences for offspring health.

Funding: MRC, BHF