Research
CTR Bioinformatics Facility
Providing bioinformatics support and teaching for the groups within the CTR. Examples of supported bioinformatics:
Sequencing
- RNA
- Single cell
- whole genome/targetted
- methylation (mC and hmC)
Structure/Function
- RNA structure prediction (2D & 3D) and motif discovery
- Protein alignments, structure prediction and interaction analysis
CTR Bioinformatics Teaching
We provide bespoke 'hands-on' bioinformatics training courses aimed at graduate students, postdocs and group leaders. Topics include RNA-Seq, DNA methylation analysis, basic R and statistics using R.
Russell Hamilton
Before joining the CTR I worked at Cambridge Epigenetix (CEGX) as a bioinformatician working on the development of epigenetics tools to enable single base resolution sequencing of methyl-cytosine (mC) and hydroxymethyl-cytosine (hmC). Prior to this I was a senior postdoc in the Department of Biochemistry at University of Oxford, working on the RNA structural motifs required for mRNA localization and their interaction with trans-acting protein factors. I developed a wide range of novel bioinformatics and computational biology approaches, including high throughput RNA sequence analysis, microscope image analysis, RNA structure prediction and genome wide motif searches.
Cambridge Big Data:
