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Centre for Trophoblast Research



CTR Bioinformatics Facility

Providing bioinformatics support and teaching for the groups within the CTR. Examples of supported bioinformatics:


  • RNA
  • Single cell
  • whole genome/targetted
  • methylation (mC and hmC)


  • RNA structure prediction (2D & 3D) and motif discovery
  • Protein alignments, structure prediction and interaction analysis


CTR Bioinformatics Teaching

We provide bespoke 'hands-on' bioinformatics training courses aimed at graduate students, postdocs and group leaders. Topics include RNA-Seq, DNA methylation analysis, basic R and statistics using R.


Russell Hamilton

Before joining the CTR I worked at Cambridge Epigenetix (CEGX) as a bioinformatician working on the development of epigenetics tools to enable single base resolution sequencing of methyl-cytosine (mC) and hydroxymethyl-cytosine (hmC).  Prior to this I was a senior postdoc in the Department of Biochemistry at University of Oxford, working on the RNA structural motifs required for mRNA localization and their interaction with trans-acting protein factors. I developed a wide range of novel bioinformatics and computational biology approaches, including high throughput RNA sequence analysis, microscope image analysis, RNA structure prediction and genome wide motif searches.


Cambridge Big Data:


Key publications: 

Publications: Google Scholar

Code Repositories: GitHub


Former Senior Research Associate and head of CTR Bioinformatics Facility
Dr Russell  Hamilton

Contact Details

+44(0)1223 333848