Research
Dr Ulla Sovio is a Principal Research Associate at the Department of Obstetrics & Gynaecology, University of Cambridge, where she studies adverse pregnancy outcomes using statistical and machine learning methods. Her research interests include clinical risk prediction and screening tool development. Ulla participated in developing a screening test using maternal, ultrasonic and placental biomarker data from the Pregnancy Outcome Prediction Study (POPS), which is currently being evaluated in an intervention trial within POPS2. In addition to being a trial statistician, Ulla is analysing omics data to further improve the identification of high risk pregnancies.
Publications
Key publications:
- Al Ghadban Y, Du Y, Charnock-Jones DS, Garmire LX, Smith GCS, Sovio U. Prediction of spontaneous preterm birth using supervised machine learning on metabolomic data: A case–cohort study. BJOG. 2024;131:908-916. DOI: 10.1111/1471-0528.17723.
- Sovio U, Gaccioli F, Cook E, Charnock-Jones DS, Smith GCS. Association between adverse pregnancy outcome and placental biomarkers in the first trimester: A prospective cohort study. BJOG. 2024;131:823-831. DOI: 10.1111/1471-0528.17691.
- Sovio U, Gaccioli F, Cook E, Charnock-Jones DS, Smith GCS. Maternal serum levels of sFlt-1 and PlGF at 20 and 28 weeks of gestational age and the risk of spontaneous preterm birth. Am J Obstet Gynecol. 2023;229:164.e1-18. DOI: 10.1016/j.ajog.2023.02.001.
- Sovio U, Clayton GL, Cook E, Gaccioli F, Charnock-Jones DS, Lawlor DA, et al. Metabolomic Identification of a Novel, Externally Validated Predictive Test for Gestational Diabetes Mellitus. J Clin Endocrinol Metab. 2022;107(8):e3479-e86. DOI: 10.1210/clinem/dgac240.
- Sovio U, Goulding N, McBride N, Cook E, Gaccioli F, Charnock-Jones DS, et al. A Maternal Serum Metabolite Ratio Predicts Large for Gestational Age Infants at Term: A Prospective Cohort Study. J Clin Endocrinol Metab. 2022;107(4):e1588-e97. DOI: 10.1210/clinem/dgab842.
- Sovio U, Goulding N, McBride N, Cook E, Gaccioli F, Charnock-Jones DS, et al. A maternal serum metabolite ratio predicts fetal growth restriction at term. Nat Med. 2020;26:348-353. DOI: 10.1038/s41591-020-0804-9.
- Sovio U, McBride N, Wood AM, Masconi KL, Cook E, Gaccioli F, et al. 4-Hydroxyglutamate is a novel predictor of pre-eclampsia. Int J Epidemiol. 2020;49(1):301-311. DOI: 10.1093/ije/dyz098.
- All publications:
