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Centre for Trophoblast Research
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Aim 1: The importance of placental research
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Placental hormones and pregnancy health in obese mothers
Understanding the nature and role of placental endocrine function in materno-fetal resource allocation during pregnancy
Genetic and molecular mechanisms of placental angiogenesis
Placental endoplasmic reticulum stress in maternal endothelial dysfunction; a model for pre-eclampsia
Improving placental energy metabolism and obstetric outcome in pathological pregnancies – lessons from high-altitude populations
Deciphering the role of the imprinted gene Rtl1/Peg11 in the placenta
Placento-fetal hypoxia and preeclampsia
Microfluidic devices for the study of human trophoblast invasion
Manipulating epigenetic reprogramming in vivo and its role in extraembryonic tissue function
How is offspring immunity set during development?
Embryonic and extraembryonic partnership: requisite for successful pregnancy
Novel regulators of trophoblast stem cell potential
An Evolutionary Approach to Understanding Transcriptional Control in the Human Placenta Co-supervised by Dr Paul Flicek, European Bioinformatics Institute (EBI, Hinxton)
Single cell sequencing of the placenta: Professor Steve Charnock-Jones
Computational analysis of next-generation sequencing methylation data
Developmental Regulation of the Placental Prolactin-Growth Hormone Gene Families in the Placenta
Mitochondrial function during pregnancy in a model of abnormal folate metabolism
Developmental origins of heart disease
Maternal signalling to oocytes and programming of offspring development and physiology
How to build a primate: towards a synthetic model for primate embryogenesis
Tissue innate immunity in the womb and reproduction
Stem cell biology of the fetal-maternal interface
Uncovering epigenetic regulation in the human placenta
Early development of the human placenta; potential role of the endometrial gland secretions
Epigenetic mechanism behind transgenerational inheritance
Folate metabolism and regulation of hematopoiesis during pregnancy
Making sense of complexity: how do tissue lymphocytes work in the uterus?
The effects of abnormal folate metabolism on placenta form and function
Multivariate statistical modelling to characterise phenotypes of human placental dysfunction.
Analysis of epigenetic and genomic stability in model of abnormal folate metabolism
Trophoblast cell migration into maternal tissues
Functional role of non-CpG methylation in human placenta
Metabo-Devo of the placenta: Understanding the metabolic determinants of early placental development Supervisors: Dr Irving Aye, Professor Stephen Charnock-Jones
Epigenetic regulation of cell fate decisions in mammalian development
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Images of human implantation
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The Human Placenta Project: In Depth feature in Science magazine
The Human Placenta Project: Video recording of launch meeting
Medawar and the Immunological paradox of pregnancy – 60 years on: podcasts from the Centre's 2013 meeting summary
CTR podcast: Understanding the placenta: the key to healthy life
CTR webinar: Placental stereology; from sections to morphometric diffusing capacity
CTR publication: The Placenta and Human Developmental Programming
Placenta supplement: Maternal-Fetal Resource Allocation
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Silvia D'Ippolito
Centre for Trophoblast Research
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Placental Biology Course
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Silvia D'Ippolito
