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Centre for Trophoblast Research



Research summary
Our hypothesis states that oxidative stress underlies the molecular basis via which prenatal hypoxia contributes to the developmental programming of cardiovascular disease. My research involves investigating the effects of complicated pregnancy, such as prenatal hypoxia, on the offspring heart function. This work offers insight to the potential mechanisms that underlies this programming process, which may lead to development of novel clinical interventions.


Funding: British Heart Foundation


Key publications: 

1. Niu Y, Evans RD. Myocardial metabolism of triacylglycerol-rich lipoproteins in type 2 diabetes. Journal of Physiology, 2009,Jul 1;587(Pt 13):3301-15.

2. Niu Y, Evans RD. Metabolism of very-low-density lipoprotein and chylomicrons by streptozotocin-induced diabetic rat heart: effects of diabetes and lipoprotein preference. American Journal of Physiology- Endocrinology and Metabolism, 2008, 295(5):E1106-16.

3. Niu Y, Hauton D, Evans RD. Utilization of triacylglycerol-rich lipoproteins by the working rat hearts: routes of uptake and metabolic fate. Journal of Physiology, 2004,558.1:225-237.

Research Associate

Contact Details

+44 (0)1223 333816
Not available for consultancy