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Centre for Trophoblast Research

 

CTR Bioinformatics

 

The CTR offers a bioinformatics facility for members

To request work be undertaken by the bioinformatics team, please download the form below and send to the CTR Administrator
 

YOU CAN DOWNLOAD THE PROJECT REQUEST FORM HERE

 

 

Examples of the type bioinformatics support provided:

Experimental Design

  • Replicates (biological vs technical)
  • Sequencing choices (read length, depth etc)

RNA-Seq

  • Differential gene expression
  • Isoform expression
  • Single cell sequencing (e.g. DROP-Seq) 

Whole genome / Targetted sequencing

  • Variant calling

Methylation Sequencing

  • Whole genome / targetted sequencing
  • Bisulfite (mC+hmC), oxidative bisulfite (mC), (h)MeDIP
  • DMR calling
  • Illumina 450K & EPIC array data analysis

RNA structure  / RNA Interactions

  • Prediction (2D and 3D)
  • RNA motif discovery and searching
  • RNA structure homology searching

Protein alignments / structure / interactions

  • Multiple sequence alignments
  • Homology modeling
  • SILAC analysis

Microscopy Image Analysis

  • Particle tracking 

Training/Teaching

  • Bespoke training (e.g. NGS Analysis, Introduction to Linux)