The CTR offers a bioinformatics facility for members

Examples of the type bioinformatics support provided:

Experimental Design

• Replicates (biological vs technical)
• Sequencing choices (read length, depth etc)

RNA-Seq

• Differential gene expression
• Isoform expression
• Single cell sequencing (e.g. DROP-Seq) 

Whole genome / Targetted sequencing

• Variant calling

Methylation Sequencing

• Whole genome / targetted sequencing
• Bisulfite (mC+hmC), oxidative bisulfite (mC), (h)MeDIP
• DMR calling
• Illumina 450K & EPIC array data analysis

RNA structure  / RNA Interactions

• Prediction (2D and 3D)
• RNA motif discovery and searching
• RNA structure homology searching

Protein alignments / structure / interactions

• Multiple sequence alignments
• Homology modeling
• SILAC analysis

Microscopy Image Analysis

• Particle tracking 

Training/Teaching

• Bespoke training (e.g. NGS Analysis, Introduction to Linux)

Contact Russell Hamilton (rsh46@cam.ac.uk) for more details