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Centre for Trophoblast Research

 

 

Course schedule

 

2022 Course schedule:

Day 1 - History, development, & Novel Technologies
Day 2 - Placental Cell Isolation, Culture & Immunology  

Day 3 - Placental Cell Biology, Histology & Pregnancy
Day 4 - Placental Physiology & Metabolism,  (Pr-booked) Fellowship Workshop (11:00 - 13:00 hrs. BST)
Day 5 - Animal models & Clinical Approaches

Daily Q&A sessions will take place on each of the course days 1 - 5, July 11 - 15, from 16:30 - 18:30 hrs. UK BST. (These sessions will be recorded and available shortly afterwards).

 

11th July 2022

 

 

Day 1 - Histoy, Development, & Novel Technologies

 

DURATION

CONTENT

SPEAKER

10 min

Introduction

Kathy Niakan

  History of human embryos Nick Hopwood

 

 

Human placental structure and development

Graham Burton

 

Cell lineage segregations in primate embryogenesis

Thorsten Boroviak

 

Human trophectoderm initiation and genome editing

Kathy Niakan

 

Principles of self-assembly of natural and stem cell embryos

Magdalena Zernicka-Goetz

 

Epigenetic mechanisms

Claire Senner

 

Multi-omics

Courtney Hanna

 

Mouse placental structure and development

Erica Watson

 

Mouse embryo and placenta practical

Erica Watson

  Mouse morula and blastocyst isolation practical Thorsten Boroviak

18:30h BST start

 

 

Live Q&A session

Part I: live presentations of selected abstracts

 

Part II: Q&A

 

 Selected participants

 

Lecturers from the day

       

 

 

12th July 2022

                                                                                                                                                      

Day 2 - Placental Cell Isolation, Culture & Immunology

 

DURATION

CONTENT

SPEAKER

 

Evolutionary aspects of human pregnancy

Ashley Moffett

 

The role of uterine NK cells in regulating placentation

Andrew Sharkey

 

Principles of cell isolation and methods to identify cells from the human placenta and decidua

Andrew Sharkey

 

Cell isolation and sorting practical

Naomi McGovern & Anna Appios

  Stem cells and cell lines Margherita Turco
  Placental and endometrial organoids practical Margherita Turco

18:30h BST start

 

 

 

Live Q&A session

Part I: live presentations of selected abstracts

 

Part II: Q&A

 

Selected participants

 

Lecturers from the day

 

 

 

13th July 2022

 

Day 3 - Placental Cell Biology, Histology & Pregnancy

 

DURATION

CONTENT

SPEAKER

 

Trophoblast invasion and spiral artery remodelling

Steve Charnock-Jones

 

Placental angiogenesis

Steve Charnock-Jones

  Clinical study design Gordon Smith
  Immune genes and cells in pregnancy Francesco Colucci
  Isolation of term trophoblast cells practical Irving Aye
  Placental explant isolation and culture practical Tereza Cindrova-Davies

 

Human placenta histology (Boyd Collection slides) and comparative animal placental histology practical

Tereza Cindrova-Davies

16:30h BST start

 

 

Live Q&A session

Part I: live presentations of selected abstracts

 

Part II: Q&A

 

Selected participants

 

Lecturers from the day

 

 

 

14th July 2022

 

Day 4 - Placental physiology & Metabolism, fellowship Workshop

 

DURATION

CONTENT

SPEAKER

  Trophoblast fusion, apoptosis, and senescence Graham Burton
  Placental transport Abby Fowden

 

Placental endocrine function

Amanda Sferruzzi-Perri

 

Placental metabolism

Andrew Murray

 

Placental mitichondrial respiration practical

Andrew Murray

2h

11 am – 1 pm BST

Fellowship application workshop

(25 participants limit)

Live session, which needs to be pre-booked. (Attendees will be sent a Zoom link)

Facilitated by: 

Amanda Sferruzzi-Perri &

Miguel Constáncia

 

18:30h BST start

 

 

Live Q&A session

Part I: live presentations of selected abstracts

 

Part II: Q&A

 

Selected participants

 

Lecturers from the day

 

 

 

15th July 2022

 

Day 5 - Animal models and clinical approaches

 

DURATION

CONTENT

SPEAKER

1h

Congenital Infection

Naomi McGovern

1h

Mouse genetic models of placental function

Miguel Constáncia

1h

Developmental programming

Dino Giussani

1h

Volume and Vascularity: Can ultrasound unlock the secrets of the first trimester placenta?

Sally Collins

18:30h BST start

1.5h

 

Live Q&A session

Part I: live presentations of selected abstracts

 

Part II: Q&A

 

Selected participants

 

Lecturers from the day

 

 

 

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Summary of Day 1-5 2022 schedules:

Day 1 - History, Development, & Novel Technologies
Day 2 - Placental Cell Isolation, Culture & Immunology

Day 3 - Placental Cell Biology, Histology & Pregnancy
Day 4 - Placental Cell Culture & Immunology
Day 5 - Animal models and clinical approaches