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Centre for Trophoblast Research

 

Course schedule

 

Day 1 - Placental Cell Culture & Novel Technologies
Day 2 - Placental Cell Culture & Immunology

Day 3 - Placental Cell Biology and History of Human Embryos
Day 4 - Placental Physiology, Bioinformatics and Data Driven Technologies
Day 5 - Animal models and clinical approaches

 

5th July 2021

 

 

Day 1 - Placental Cell Culture & Novel Technologies

 

Duration

Content

Speaker

 

10 min

Introduction

Kathy Niakan

 

1h

 

Human placental structure and development

Graham Burton

1h

Comparative placentation and evolution

Mick Elliott

 

1h

Cell lineage segregation
(non-human primate placental development)

 

Thorsten Boroviak

 

1h

Human trophectoderm initiation and genome editing

 

Kathy Niakan

1h

Data drive technologies in embryo selection in IVF

Lucy van de Wiel

1h

Stem cell-based embryo models

Magdalena Zernicka-Goetz

 

1h

Epigenetic mechanisms

Multi-omics

 

Claire Senner

 

Courtney Hanna

 

1h

Mouse placental structure and development

Erica Watson

 

1h

Anatomy and Development practical (mouse placenta) – different stages of embryos & placentas.

 

Erica Watson & Thorsten Boroviak

                                                                 

1.5h

 

Live Q&A session

Part I: live presentations of 4 selected abstracts

 

Part II: Q&A

 

 

4 selected participants

 

All lecturers

       

 

 

6th July 2021

                                                                                                                                                      

Day 2 - Placental Cell Culture & Immunology

 

Duration

 

Content

Speaker

1h

Immune genes and cells in pregnancy

Andrew Sharkey

 

1h

Clinical and evolutionarily aspects of immunology of placentation

 

Ashley Moffett

 

1h

Immune genes and cells in pregnancy

 

Francesco Colucci

1.5h

Cell isolation and sorting practical

 

Principles of cell isolation and methods to identify cells from the human placenta and decidua

 

Naomi McGovern & Anna Appios

 

Andrew Sharkey

 

1h

Stem cells and cell lines

Margherita Turco

 

1h

Placental and endometrial organoids practical

 

Margherita Turco

 

1.5h

 

Live Q&A session

Part I: live presentations of 4 selected abstracts

 

Part II: Q&A

 

4 selected participants

 

All lecturers

 

 

 

7th July 2021

 

Day 3 - Placental Cell Biology and History of Human Embryos

 

Duration

 

Content

Speaker

1h

Trophoblast invasion and spiral artery remodelling

 

Steve Charnock-Jones

 

1h

Placental transport

Abby Fowden

 

1.5h

Human placenta histology practical

(the Boyd collection)

Comparative placenta slides

 

Tereza Cindrova-Davies

 

1h

Placental endocrinology

Amanda Sferruzzi-Perri

 

1h

Placental metabolism

Andrew Murray

 

1.45h

Respirometry practical (Oroboros system)

(45 min)

 

 

Placental explant isolation and culture practical (30 min)

 

 

Isolation of term trophoblast cells practical

(30 min)

 

 

Andrew Murray

 

 

 

Tereza Cindrova-Davies

 

 

 

Irving Aye

 

 

1h

History of human embryos

Nick Hopwood

 

1.5h

 

Live Q&A session

Part I: live presentations of 4 selected abstracts

 

Part II: Q&A

 

4 selected participants

 

All lecturers

 

 

 

8th July 2021

 

Day 4 - Placental Physiology, Bioinformatics and Data Driven Technologies

 

Duration

Content

Speaker

 

1h

Placental angiogenesis

 

Steve Charnock-Jones

 

1h

Trophoblast fusion, apoptosis, and senescence

Graham Burton

 

1h

Clinical study design

 

Gordon Smith

 

4h

Bioinformatics Practical / Workshop

 

Russell Hamilton

 

2h

11 am – 1 pm GMT

Fellowship application workshop

 

(25 participants)

Live session, which needs to be pre-booked

Facilitated by: 

 

Amanda Sferruzzi-Perri &

Miguel Constáncia

 

1.5h

 

Live Q&A session

Part I: live presentations of 4 selected abstracts

 

Part II: Q&A

 

4 selected participants

 

All lecturers

 

 

 

9th July 2021

 

Day 5 - Animal models and clinical approaches

 

Duration

Content

Speaker

 

1h

Congenital Infection

Naomi McGovern

 

1h

Mouse genetic models of placental function

 

Miguel Constáncia

 

 

 

1h

Developmental programming

 

Dino Giussani

 

1h

Volume and Vascularity: Can ultrasound unlock the secrets of the first trimester placenta?

 

Sally Collins

 

1.5h

 

Live Q&A session

Part I: live presentations of 4 selected abstracts

 

Part II: Q&A

 

4 selected participants

 

All lecturers